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GREGORY
W. O'NEIL
Associate Professor
Organic
Chemistry
Education
B.S. Chemistry, Boston College, 2002.
Ph.D. Organic Chemistry, University of Colorado, 2006
Alexander von Humboldt Postdoctoral Fellowship, Max-Planck Institut fur
Kohlenforschung, 2006-2008.
Research Interests
Our group specializes in the enantioselective synthesis of biologically and environmentally important natural products. Our research may be divided into two broad categories: (1) the synthesis of structurally interesting and biologically/environmentally compelling small molecule natural products and (2) the development of new synthetic methods with applications in natural product synthesis.
Recent Publications
O'Neil, G. W.; Carmichael, C. A.; Goepfert, T. J.; Fulton, J. M.; Knothe, G.; Lau, C. P-L. Lindell, S. R.; Mohammady, N. G-E.; Van Mooy, B. A. S. Reddy, C. M. "Beyond Fatty Acid Methyl Esters: Expanding the Renewable Carbon Profile with Alkenones from Isochrysis sp." Energy Fuels, 2012, 26, 2434–2441.
Tran, A. B.; Melly, G.; Doucette, R.; Ashcraft, B.; Sebren, L.; Young, J.; O'Neil, G. W. "Synthesis and activity of the archazolid western hemisphere." Org. Biomol. Chem. 2011, 9, 7671.
Storvick, J. K.; Ankoudinova, E.; King, B. R.; Van Epps, H.; O'Neil, G. W. "Total synthesis of haminol A: An analysis of vinylpyridine metathesis reactivity." Tetrahedron Lett. 2011, 52, 5858.
Volz, E. O.; O'Neil, G. W. "Chemoselective Samarium-Mediated Benzoyloxysulfone Eliminations." J. Org. Chem. 2011, 76, 8428.
Carter, K. P., Moser, D. J.; Storvick, J. M.; O'Neil, G. W. "A masked-alkene metathesis-based synthesis of isopulo'upone." Tetrahedron Lett. 2011, 52, 4494.
O'Neil, G. W.; Miller, M. M.; Carter, K. P. "Direct Conversion of ß-Hydroxyketones to Cyclic Disiloxanes." Org. Lett. 2010, 12, 5350.
O'Neil, G. W.; Black, M. J. "A Synthesis of the C3-C15 Fragment of the Archazolids." Synlett, 2010, 107.
O'Neil, G. W.; Moser, D. J.; Volz, E. O. "Metathesis Reactions of ß-Acyloxysulfones: Synthesis of 1,6- and 1,7-Dienes." Tetrahedron Lett. 2009, 50, 7355.
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